|
KMID : 0942820080070020120
|
|
Journal of Korean Brain Tumor Society
2008 Volume.7 No. 2 p.120 ~ p.126
|
|
|
Clinical Manifestations and Surgical Outcome of Pituitary Apoplexy
|
|
Jeon Hong-Jun
Kang Jeong-Han
Cho Byung-Moon
Kim Moon-Kyu
Oh Sae-Moon
Park Se-Hyuck
|
|
|
Abstract
|
|
|
Objective: Pituitary apoplexy is a well-described clinical syndrome resulting from pituitary hemorrhage, hemorrhagic infarction, or infarction of pituitary adenoma. We reviewed surgically-treated 14 cases presenting with pituitary apoplexy.
Materials & Methods: From 2003 to 2008, We retrospectively analyzed clinicoradiological features, hormonal status and pathological findings of 14 patients with pituitary apoplexy. Thirteen out of 14 patients were operated on by transshenoidal approach and the other 1 patient by transcranial approach.
Results: The average age of patients was 51.1 years. There were 3 females and 11 males. The average time of presentation was14.5 days. Headache was the most common presenting symptom(78.6%), followed by diminished visual acuity and field(42.9%), ocular palsies(31%), and altered consciousness(7.1%) respectively. Eleven patients had non-functioning macroadenomas and the other 3 had growth hormone-secreting macroadenoma. Among non-functioning tumors, 6 patients showed evidence of hypopituitarism and 5 patients had normal pituitary function. After surgery, headache and ocular palsies improved in all patients. Howerver, visual acuity improved in 4 out of 6 patients and visual field in 5 out of 6 patients. In endocrine study, 4 patients with preoperative hypopituitarism recovered but 2 patients with preoperative normal pituitary function worsened to need hormonal therapy. Histological examination showed hemorrhage in 13 patients and infarction in 1 patient.
Conclusion: Pituitary apoplexy should be included in the differential diagnosis of the patients complaining of sudden headache, visual disturbance and altered consciousness. High dose of corticosteroid administration and early surgical decompression of pituitary apoplexy showed good outcomes.
|
|
|
KEYWORD
|
|
|
Pituitary apoplexy, Clinical outcome, Surgical outcome
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|